Home Printer Drivers Epson Expression Premium XP-645 driver, Software Download

Epson Expression Premium XP-645 driver, Software Download

The Epson Expression Premium XP-645 model is an exceptional choice among multipurpose printers with the ability to print, copy, and scan documents to produce excellent output. The machine supports up to 360 nozzles of black and 180 nozzles for color printing in the nozzle configuration. Besides, the minimum ink droplet size is up to 1.5 picolitres (pl) but with variable sized droplet technology. Also, ink technology is the Claria Premium ink while supporting home and photo devices.

Epson Expression Premium XP-645 printer driver Supported Windows Operating Systems

Supported OS: Windows 10 32-bit, Windows 10 64-bit, Windows 8 32-bit, Windows 8 64-bit, Windows 7 32-bit, Windows 7 64-bit, Windows Vista 32-bit, Windows Vista 64-bit, Windows XP 32-bit, Windows XP 64-bit
Printer Driver for Windows XP Vista 7 8 and 10 32 Bit.exe40.82 MB Download
Printer Driver for Windows XP Vista 7 8 and 10 64 Bit.exe43.01 MB Download
Scan Driver for Windows XP Vista 7 8 and 10.exe51.94 MB Download
Scan Updater for Windows 10.exe733.95 kB Download

Epson Expression Premium XP-645 driver Supported Mac Operating Systems

Supported OS: macOS Big Sur 11.x, Mac OS Catalina 10.15.x, macOS Mojave 10.14.x, macOS High Sierra 10.13.x, macOS Sierra 10.12.x, Mac OS X El Capitan 10.11.x, Mac OS X Yosemite 10.10.x, Mac OS X Mavericks 10.9.x, Mac OS X Mountain Lion 10.8.x, Mac OS X Lion 10.7.x, Mac OS X Snow Leopard 10.6.x, Mac OS X Leopard 10.5.x
Printer Driver for mac OS X 10.5 to 10.15 and 11.x .dmg108.23 MB Download
Scan 2 Driver for mac OS X 10.5 to 10.15 and 11.x .dmg24.94 MB Download
Scan Driver for mac OS X 10.5 to 10.13.dmg18.07 MB Download
Uninstall Center for mac OS X 11.x and 10.15.dmg1.17 MB Download


When printing with this machine, the print quality resolution reaches 5760 x 1440 dots per inch (dpi) at the best performance level. Furthermore, at the ISO/IEC 24734 standard mode, printing with this device has a speed of 13 pages per minute (ppm) for monochrome documents. Simultaneously, color documents at the same print mode have a print rate of 10 ppm. However, the standard print rate is about 32 ppm for monochrome and color documents. More so, it takes about 20 seconds to print on an Epson premium glossy photo paper.

It can also scan documents at both simplex and duplex modes as a multipurpose device. The former refers to scan only one page of the document per time, while the latter refers to scan the two sides of a paper. Single-sided scanning on an A4 report for both color and black and white is up to 300 dots per inch (dpi). However, the optical resolution reaches up to 1200 x 2400 dpi while using the scanner’s contact image sensor (CIS) element.

There are two trays in this device in terms of paper handling, with each supporting standard paper sizes. For instance, the paper sizes include A4, A5, A6, B5, C6, Envelopes, letter, and legal. It also has a multifunction paper tray that can hold up to 100 plain paper sheets. Simultaneously, the same tray will hold about 20 photo sheets. Download Epson Expression Premium XP-645 driver from Epson Website

[Installation Instructions] How to Download / Installation procedure

Note: Do not connect the USB cable until requested by the installer. If you connect to the network, make sure the network cable is connected before running the installer


  • Close all software programs running on your computer.
  • Turn on the printer.
  • Click the Download button on this page.
  • Click the downloaded file. The files will be extracted and the installation process will automatically begin.
  • Follow the instructions on the screen to continue and complete the installation.


  • Download the file. For the location where the file is saved, check the computer settings.
  • Double-click the downloaded file and mount it on the Disk Image.
  • Double-click the mounted Disk Image.
  • Double-click the packaged file in the folder. Installation starts automatically.

To install later, select Save in step 4 and choose a location on your hard disk. When ready to install, search and double-click the file. This will automatically extract and start the installation process. Follow the instructions on the screen to continue the installation.

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